Logo for: Find A Kidney

Is there a Cure for Kidney Failure?

Clark Kensinger, MD, NKR Medical Board, Surgical Director, Kidney Transplant, Piedmont Healthcare

Kidney failure, also known as end-stage renal disease (ESRD), occurs when your kidneys are no longer able to perform their essential functions, such as filtering waste and excess fluids from your blood. If you or a loved one are facing kidney failure, you may wonder: Can kidney failure be cured?

While there isn’t a direct “cure” for kidney failure at this time, there are treatments and management strategies that can help you live well and even extend your life.

Treatment Options for Kidney Failure

Although kidney failure itself may not be reversible, there are two main treatments that can help manage the condition: dialysis and kidney transplantation.

1. Dialysis

Dialysis is a life-saving treatment that performs the work your kidneys no longer can. There are two types of dialysis:

Hemodialysis: This type of dialysis uses a machine to filter your blood outside your body. A needle is inserted into a vein, and your blood is sent through a filter that removes waste, excess fluids, and salt. The cleaned blood is then returned to your body.

Peritoneal Dialysis: This treatment uses the lining of your abdomen (the peritoneum) as a natural filter. A sterile solution is placed into your abdomen through a catheter, where it absorbs waste and excess fluids. After a few hours, the solution is drained and replaced with fresh fluid.

Dialysis helps maintain fluid balance and prevents dangerous buildup of waste products in the body, but it is not a cure—it is a form of ongoing treatment. It’s also not a good long-term solution. The mortality rate for patients on hemodialysis is 10 to 20 times higher than the general population—about 9% per year—with five-year survival rate of less than 50% on average. Peritoneal dialysis patients have five-year survival rates of 60% to 70%.

2. Kidney Transplant

A kidney transplant is the only treatment that offers the potential to restore kidney function permanently. A transplant involves receiving a healthy kidney from a living or deceased donor. After a successful transplant, the new kidney can perform the work of the failed kidneys, allowing you to live a normal, healthy life.

However, kidney transplants are not always an option for everyone. Factors like overall health, compatibility with a donor kidney, and the availability of a donor can affect whether transplant is possible. Even after a transplant, the body’s immune system can sometimes reject the new kidney, which requires careful monitoring and ongoing medication.

While there is no outright cure for kidney failure, treatments like dialysis and kidney transplantation can help manage the condition and improve quality of life. If you or a loved one are facing kidney failure, discussing treatment options with a healthcare provider can help determine the best path forward to maintain health and well-being.